Lesson 4.6.1.5

4.6.1.5 Inherited disorders Quiz: AQA Combined Science, Unit 6

20 questions

Written by Revision Ninja · Last reviewed 11 October 2026

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Lesson 4.6.1.5, Inherited disorders: 20 multiple choice questions for the AQA GCSE Combined Science (8464), Unit 6: Inheritance, variation and evolution, written with Revision Ninja.

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The 20 questions

  1. Polydactyly is caused by which type of allele?

    • Environmental factor only
    • Missing chromosome
    • Recessive
    • Dominant

  2. Cystic fibrosis is caused by which type of allele?

    • Loss of a chromosome
    • Infection only
    • Recessive
    • Dominant

  3. Cystic fibrosis is a disorder of which structure?

    • Nerve sheaths
    • Cell membranes
    • Bone marrow
    • Blood plasma

  4. What genetic allele causes polydactyly?

    • Recessive allele
    • Codominant allele
    • Mutated protein
    • Dominant allele

  5. What issues must be considered regarding embryo screening?

    • Economic and ethical
    • Atomic and nuclear
    • Magnetic and thermal
    • Chemical and physical

  6. What benefit may embryo screening and gene therapy provide?

    • Remove mutations
    • Increase height
    • Cure ageing
    • Alleviate suffering

  7. Inherited disorders are caused by the inheritance of what?

    • Certain alleles
    • Bacterial infection
    • Environmental toxins
    • Random mutations only

  8. Which allele combination must a person with polydactyly have?

    • Only mutated DNA
    • No alleles
    • Dominant allele
    • Two recessive alleles

  9. Two parents without polydactyly (both homozygous recessive) have a child. What is the probability the child has polydactyly?

    • 25%
    • 0%
    • 100%
    • 50%

  10. Two parents are both heterozygous for polydactyly. What is the probability a child has polydactyly?

    • 75%
    • 50%
    • 100%
    • 25%

  11. Two parents are both carriers of cystic fibrosis. What is the probability a child has the condition?

    • 75%
    • 50%
    • 0%
    • 25%

  12. A child inherits cystic fibrosis from both parents. What genotype does the child have?

    • Homozygous dominant
    • Heterozygous
    • Homozygous recessive
    • Dominant and recessive

  13. A parent with polydactyly (heterozygous) and a parent without it (homozygous recessive) have a child. What is the probability of polydactyly?

    • 25%
    • 0%
    • 75%
    • 50%

  14. What is selected during successful embryo screening?

    • Mutated cells
    • Healthy embryos
    • Bacterial plasmids
    • Recessive zygotes

  15. What is a major concern associated with embryo screening?

    • Energy transfer
    • Cell division
    • Ethical issues
    • Chromosome loss

  16. Why do dominant disorders appear in every generation?

    • One allele needed
    • Recessive masking
    • Environmental triggers
    • Two alleles needed

  17. Why can recessive disorders like cystic fibrosis skip generations?

    • Alleles disappear
    • Carriers show nothing
    • Dominant masking
    • Mutations reverse

  18. What does evaluating embryo screening involve balancing?

    • Suffering versus ethics
    • Mass versus energy
    • Speed versus time
    • Voltage versus current

  19. One parent is a cystic fibrosis carrier (Cc) and the other is not (cc). What is the probability of a child with cystic fibrosis?

    • 100%
    • 25%
    • 0%
    • 50%

  20. Which parental genotypes guarantee a child with cystic fibrosis?

    • One normal parent
    • Two heterozygous parents
    • Two recessive parents
    • Two dominant parents

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