Lesson 3.8.3.1

3.8.3.1 Genome sequencing and non-coding DNA Quiz: AQA Biology, Unit 8

20 questions

Written by Revision Ninja · Last reviewed 11 October 2026

In partnership with Revision Ninja

Lesson 3.8.3.1, Genome sequencing and non-coding DNA: 20 multiple choice questions for the AQA Biology (7402), Unit 8: The control of gene expression, written with Revision Ninja.

Host it live on the board and students join with a game code on their own devices, or revise alone with Free Play. The answers are revealed in the game.

Host this setFree Play

The 20 questions

  1. Genome sequencing projects have determined the full DNA base sequences of which group?

    • Prokaryotes exclusively
    • Viruses alone
    • Many diverse organisms
    • Only human beings

  2. What set of proteins expressed by an organism can be directly determined from a simple genome?

    • The transcriptome
    • The proteome
    • The metabolome
    • The epigenome

  3. Which molecules identified from a pathogen's proteome can be used to develop vaccines?

    • Glycolipids
    • Surface antigens
    • Plasmids
    • Phospholipids

  4. What feature of complex organisms prevents direct translation of the genome into the proteome?

    • Circular DNA
    • Non-coding DNA
    • Double helices
    • Phosphodiester bonds

  5. How have modern DNA sequencing methods changed compared to early techniques?

    • They use gels
    • They are automated
    • They use radioisotopes
    • They are manual

  6. Which part of a pathogen's proteome is targeted by the host immune system?

    • Antigenic proteins
    • Nuclear membranes
    • Non-coding RNA
    • Capsule lipids

  7. Why is proteome identification easier in prokaryotes than in complex eukaryotes?

    • Multiple chromosomes
    • More introns
    • Larger genomes
    • Less non-coding DNA

  8. Which genomic regions directly code for amino acid sequences in proteins?

    • Introns
    • Terminators
    • Exons
    • Promoters

  9. What is a major advantage of automated DNA sequencing over manual methods?

    • Slower processing
    • Longer primers
    • Lower cost
    • Higher mutation rates

  10. What is defined as the full range of proteins that a cell can produce?

    • The exome
    • The genome
    • The proteome
    • The transcriptome

  11. A pathogen has 40 genes, of which 10 encode surface proteins that are candidate antigens. What percentage of its genes encode candidate antigens?

    • 4 per cent
    • 40 per cent
    • 10 per cent
    • 25 per cent

  12. What term describes non-coding DNA sequences found within eukaryotic genes?

    • Exons
    • Codons
    • Introns
    • Anticodons

  13. Which type of organism has a genome that is easiest to directly relate to its proteome?

    • Eukaryotic plant
    • Prokaryotic bacterium
    • Mammalian species
    • Multicellular fungus

  14. Why can sequencing a human genome not reveal all proteins produced at any given moment?

    • Absence of tRNA
    • Regulatory genes
    • Lack of ribosomes
    • Fixed expression

  15. A genome of 4 million bases is 88 per cent coding. How many coding bases does it contain?

    • 4 400 000
    • 480 000
    • 3 520 000
    • 3 000 000

  16. What field of medicine relies heavily on rapid, automated high-throughput genome sequencing?

    • Homeopathy
    • Personalised medicine
    • Herbal remedies
    • Traditional acupuncture

  17. Put these stages in the most likely order: 1 test candidate antigens, 2 predict proteins from coding regions, 3 sequence the genome, 4 identify coding regions. Which sequence is correct?

    • 4, 3, 2, 1
    • 1, 2, 3, 4
    • 3, 4, 2, 1
    • 2, 3, 1, 4

  18. What controls whether a specific protein is synthesised from DNA in response to cellular conditions?

    • Stop codons
    • Peptide bonds
    • Regulatory elements
    • Histone tails

  19. Which non-coding DNA sequences are removed during pre-mRNA splicing in eukaryotic cells?

    • Poly-A tails
    • Promoters
    • Exons
    • Introns

  20. What feature of complex organisms makes predicting their proteome directly from genome sequencing difficult?

    • Single circular chromosome
    • Universal genetic code
    • Lack of introns
    • Non-coding DNA

All AQA Biology quizzes