Lesson 4.6.1.7

4.6.1.7 Inherited disorders Quiz: AQA Biology, Unit 6

20 questions

Written by Revision Ninja · Last reviewed 11 October 2026

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Lesson 4.6.1.7, Inherited disorders: 20 multiple choice questions for the AQA GCSE Biology (8461), Unit 6: Inheritance, variation and evolution, written with Revision Ninja.

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The 20 questions

  1. Polydactyly is caused by which type of allele?

    • Dominant
    • Recessive
    • Co-dominant
    • Sex-linked recessive

  2. Cystic fibrosis is caused by which type of allele?

    • Dominant
    • Polygenic
    • Recessive
    • Mutant gamete

  3. What main physical characteristic is caused by the inherited disorder polydactyly?

    • Thick sticky mucus
    • Vision impairment
    • Extra fingers or toes
    • Shortened limbs

  4. Cystic fibrosis is described as a disorder of which structures?

    • Red blood cells
    • Cell membranes
    • Bone marrow
    • Nerve endings

  5. Which type of allele causes the inherited disorder polydactyly?

    • Dominant allele
    • Sex-linked allele
    • Recessive allele
    • Codominant allele

  6. How many copies of the recessive allele are needed for a person to have cystic fibrosis?

    • Two
    • None
    • One
    • Three

  7. What is a person called who carries one cystic fibrosis allele without having symptoms?

    • Homozygous recessive
    • Affected individual
    • A carrier
    • Dominant phenotype

  8. Which three main categories of issues must be considered when evaluating embryo screening?

    • Genetic, cellular, atomic
    • Environmental, climatic, geographical
    • Economic, social, ethical
    • Physical, chemical, biological

  9. Which medical technology can be used alongside embryo screening to alleviate suffering from inherited disorders?

    • Gene therapy
    • Radiotherapy
    • Organ transplantation
    • Vaccination

  10. What should be made when evaluating the ethical, social, and economic aspects of embryo screening?

    • Absolute guarantees
    • Random guesses
    • Informed judgements
    • Legal regulations

  11. Both parents carry one cystic fibrosis allele. What is the chance a child has cystic fibrosis?

    • 1 in 8
    • 1 in 4
    • 3 in 4
    • 1 in 2

  12. Which organ system does cystic fibrosis primarily affect by producing thick mucus?

    • Endocrine system
    • Nervous system
    • Respiratory system
    • Circulatory system

  13. Cystic fibrosis is a recessive disorder. What genotype must two unaffected parents of an affected child have?

    • Both heterozygous
    • Both homozygous dominant
    • One homozygous dominant
    • Both homozygous recessive

  14. What probability do children have of inheriting polydactyly if parents are Pp and pp?

    • 25%
    • 0%
    • 100%
    • 50%

  15. Why can cystic fibrosis skip generations in a family history?

    • It is dominant
    • It is environmental
    • It is recessive
    • It is non-genetic

  16. In a family where two carriers have children, how many of four children are expected to be affected by cystic fibrosis?

    • 1
    • 3
    • 2
    • 0

  17. What is the probability that a child of two carriers is also a carrier?

    • 1 in 8
    • 3 in 4
    • 1 in 4
    • 1 in 2

  18. Why does embryo screening raise ethical concerns during in vitro fertilisation?

    • Embryo selection choices
    • High financial cost
    • Membrane damage risk
    • Bacterial infection risk

  19. What type of allele causes cystic fibrosis?

    • Sex-linked
    • Codominant
    • Recessive
    • Dominant

  20. What proportion of children will be carriers if one parent has cystic fibrosis and one is homozygous dominant?

    • None
    • Three-quarters
    • All children
    • Half

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