Lesson 4.3.1.9

4.3.1.9 Discovery and development of drugs Quiz: AQA Biology, Unit 3

20 questions

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Lesson 4.3.1.9, Discovery and development of drugs: 20 multiple choice questions for the AQA GCSE Biology (8461), Unit 3: Infection and response, written with Revision Ninja.

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The 20 questions

  1. Which heart drug originates from foxgloves?

    • Insulin
    • Penicillin
    • Digitalis
    • Aspirin
  2. Which painkiller originates from willow?

    • Digitalis
    • Aspirin
    • Glucagon
    • Penicillin
  3. Who discovered penicillin from Penicillium mould?

    • Charles Darwin
    • Alexander Fleming
    • Gregor Mendel
    • Edward Jenner
  4. From which two sources were drugs traditionally extracted?

    • Plants and microorganisms
    • Animals and minerals
    • Viruses and fungi
    • Metals and gases
  5. Who synthesises most new medical drugs today?

    • Retail pharmacists
    • Pharmaceutical chemists
    • Hospital doctors
    • University students
  6. Which three main factors are new medical drugs extensively tested for?

    • Mass, volume, shape
    • Cost, colour, taste
    • Toxicity, efficacy, dose
    • Solubility, pH, age
  7. What are new medical drugs tested for in preclinical testing?

    • Sales and marketing
    • Cost and packaging
    • Colour and taste
    • Toxicity and efficacy
  8. Who takes part in clinical trials for new drugs?

    • Computer models only
    • Lab animals only
    • Human tissues only
    • Volunteers and patients
  9. What dose of a new drug is administered at the start of a clinical trial?

    • Very low dose
    • Double dose
    • Maximum dose
    • Normal therapeutic dose
  10. In a double blind trial, what do some patients receive?

    • A placebo
    • Antibiotics
    • Insulin injections
    • A new vaccine only
  11. Why are very low doses given at the start of a clinical trial?

    • To lower costs
    • To check safety
    • To speed approval
    • To test efficacy
  12. In a trial, neither the patients nor the doctors know who gets the drug. Which type of trial is this?

    • Plant extraction trial
    • Single cell trial
    • Preclinical trial
    • Double blind trial
  13. Which plant is the traditional origin of the heart drug digitalis?

    • Foxgloves
    • Poppy
    • Rosemary
    • Willow
  14. A scientist tests a drug in cell cultures to find whether it harms cells. What is being tested?

    • Toxicity
    • Dose
    • Shelf life
    • Efficacy
  15. Which stage of testing finds the optimum dose of a new drug?

    • Peer review
    • Computer modelling
    • Preclinical testing
    • Clinical trials
  16. Who evaluates trial results during peer review before publication?

    • Drug manufacturers
    • Patients
    • Healthy volunteers
    • Other scientists
  17. What is the main reason for conducting double-blind clinical trials?

    • Reduce cost
    • Prevent bias
    • Speed up trials
    • Increase dosage
  18. What is the optimum dose of a drug?

    • Highest toxic dose
    • Lowest possible dose
    • Effective and safe
    • Maximum tolerated dose
  19. Why is a very low dose of a new drug given to healthy volunteers first?

    • Check immunity
    • Test safety
    • Lower cost
    • Test efficacy
  20. Which drug used to treat heart conditions was originally extracted from foxgloves?

    • Aspirin
    • Digitalis
    • Insulin
    • Penicillin

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