Lesson 4.3.2.1

4.3.2.1 Producing monoclonal antibodies Quiz: AQA Biology, Unit 3

20 questions

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Lesson 4.3.2.1, Producing monoclonal antibodies: 20 multiple choice questions for the AQA GCSE Biology (8461), Unit 3: Infection and response, written with Revision Ninja.

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The 20 questions

  1. Monoclonal antibodies are produced from which of the following?

    • Single clone
    • Random cells
    • Stem cells
    • Multiple clones
  2. Which cells are stimulated in mice to make a particular antibody?

    • Lymphocytes
    • Guard cells
    • Liver cells
    • Neurones
  3. Which two cell types are fused together to make a hybridoma cell?

    • Nerve and gland cell
    • Red cell and bacterium
    • Lymphocyte and tumour
    • Platelet and pathogen
  4. What property does a tumour cell provide to a hybridoma cell?

    • Antibody production
    • Antigen binding
    • Phagocytosis
    • Rapid cell division
  5. What is done to a single hybridoma cell to produce large quantities of antibodies?

    • It is denatured
    • It is vaccinated
    • It is fertilised
    • It is cloned
  6. What must be done to monoclonal antibodies after collection before they are used?

    • They are heated
    • They are neutralised
    • They are cloned
    • They are purified
  7. What do monoclonal antibodies bind to?

    • Multiple different antigens
    • One specific antigen
    • Any human hormone
    • All pathogen surfaces
  8. Why can monoclonal antibodies target specific cells in the body?

    • They divide rapidly
    • They are small
    • They contain enzymes
    • They are specific
  9. Which animal's lymphocytes are used in the specification's production method?

    • Mouse
    • Fish
    • Frog
    • Rabbit
  10. Which cell type is stimulated to produce antibodies for monoclonal antibody production?

    • Bacterial cell
    • Mouse lymphocyte
    • Fungal spore
    • Human red cell
  11. Which property does a hybridoma cell inherit from its lymphocyte parent?

    • Uncontrolled growth
    • Antibody production
    • Antigen presentation
    • Rapid cell division
  12. What type of antibodies are produced by clones of a single hybridoma cell?

    • Different antibodies
    • Mixed antibodies
    • Identical antibodies
    • Variable antibodies
  13. Why are monoclonal antibodies purified before medical use?

    • Change antigen shape
    • Increase cell division
    • Remove contaminants
    • Destroy tumour cells
  14. Which type of cell provides the ability to produce antibodies when forming a hybridoma?

    • Phagocyte
    • Tumour cell
    • Lymphocyte
    • Red blood cell
  15. Monoclonal antibodies are specific to how many binding sites on an antigen?

    • Two
    • One
    • Variable
    • Multiple
  16. Why are mouse lymphocytes combined with tumour cells to produce monoclonal antibodies?

    • Increase mutation
    • Destroy bacteria
    • Produce antigens
    • Divide continuously
  17. Which cells are fused with mouse lymphocytes to produce hybridoma cells?

    • Bacterial cells
    • Tumour cells
    • Skin cells
    • Red blood cells
  18. What do mouse lymphocytes produce in response to a specific antigen?

    • Antibodies
    • Hormones
    • Pathogens
    • Antigens
  19. Monoclonal antibodies bind to specific target sites on which type of molecule?

    • Fatty acid
    • Glucose molecule
    • Protein antigen
    • Nucleic acid
  20. What does the prefix 'mono' mean in the term monoclonal antibody?

    • One
    • Many
    • Different
    • Two

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